Why are malnourished individuals more susceptible to cholera?

The increased susceptibility of malnourished individuals to cholera can be linked directly to their compromised immune function rather than the pH of their stomach. Malnutrition often leads to a decrease in the production of immune cells and antibodies, which means that the body is less equipped to fight off infections, including those caused by cholera toxins.

Additionally, malnourished individuals may experience a change in their gut microbiota. A balanced and diverse gut flora plays a crucial role in protecting against gastrointestinal infections. When individuals are malnourished, this microbial community can be disrupted, making it easier for pathogens like Vibrio cholerae to establish an infection.

Understanding this context highlights that while stomach acidity and hydration levels play roles in gastrointestinal health, they do not accurately reflect the primary reasons behind the vulnerability of malnourished people to cholera infections. The compromised immune system and disrupted gut flora are the key factors that increase the risk of severe illness.