What role do macrophages play in the immune response?

Macrophages are critical components of the immune response, primarily known for their ability to ingest and destroy pathogens through a process known as phagocytosis. They act as versatile cells that can effectively eliminate bacteria, viruses, and other foreign materials that invade the body. In addition to their phagocytic function, macrophages play a key role in activating other immune cells. After ingesting pathogens, they can present antigens on their surface, which is crucial for alerting T cells and initiating a more extensive adaptive immune response.

This multifaceted role allows macrophages to not only respond to immediate threats but also coordinate the overall immune response by communicating with other cells, thereby enhancing the body’s ability to fight infection and maintain health.